The meaning of proverbs further into the forest. The farther in the forest, the more firewood (the further in the dispute, the more words)
Proverbs of the Russian people. - M.: Fiction. V. I. Dal. 1989.
Watch what is "The farther in the forest, the more firewood." in other dictionaries:
Cf. The only case was lung ... But ... the further in the forest, the more firewood. Each afternoon, Lganya's talent became in them ... in undoubtedly bo / linse. GL Assumption. New times. Three letters. 2. CP. Will you go for good mind from here? it is seen …
Came further in Lѣs, Tѣm more than firewood (Chѣm Dalѣe in the dispute, Tѣm more words). Cf. The only one was lung ... But ... then further in Lѣs, TѣM is more than firewood. Each day Talent Lghanya became in them ... B is undoubtedly the big ... ... Large intelligent-phraseological dictionary of Michelson (original spelling)
The farther in the forest, the more partisans
The farther in the forest, so it is in fig - (from the last. The farther in the forest, the more firewood the farther events develop, the more difficulties arise; the root sounds like in the forest) source sign ... Living speech. Dictionary of spoken expressions
The farther in the forest, the third extra - (from the last. The farther in the forest, the more firewood the farther events develop, the more difficulties arise; the root sounds like in the forest) source sign ... Living speech. Dictionary of spoken expressions
The farther into the forest, the more firewood (the further in the dispute, the greater the words) cf. The only case was lung ... But ... the further in the forest, the more firewood. Each afternoon, Lganya's talent became in them ... in undoubtedly bo / linse. GL Assumption. New ... ... Mikhelson's Big Thick-Frazological Dictionary
The farther // Vlez, the greater the interest / in the forest, the more partisans - Ambassador. Before.: The further into the forest, the more firewood. What would the child be treated, just not fucked by the ambassador. Before., Makar.: What would the child be treated, just not crying., Eng .: To Fuck make love ... Explanatory dictionary of modern conversational phrases and progress
The further got, the more interest - (from the last. The farther in the forest, the more firewood the farther events develop, the more difficulties arise; the root sounds like in the forest) source sign ... Living speech. Dictionary of spoken expressions
the farther "Vlez, the closer got out ... the thicker the partisans are joke." Paroding sayings "The farther in the forest, the more firewood" ... Dictionary of Russian Argo
Union. 1. Joins turnover or attached. Run. with a comparison value, comparing whom, which l. With what is said in the main thing. Turn louder than usual. In the south of the stars brighter than in the north. The mountains were higher than someone assumed. 2 ... encyclopedic Dictionary
Books
- The shadow of light, Andrei Vasilyev. The studio "Mediakniga" presents the third audiobook of the series "A.Smolin, Witcher" of the famous Russian writer Andrei Vasilyeva - "The Shadow of Light". The book is read by a popular artist and actor ... Audiobook
- The shadow of light, Andrei Vasilyev. Everyone knows a folk proverb that stars that "the farther in the forest is the more firewood." So it really is. The larger the Beginner Witcher Alexander Smolin learns about exactly how it is arranged ...
The traditional role of a family of small interfering RNAs (MirNNA), - small RNA molecules that are not coding proteins are considered to be the repression of gene activity and in particular - protein synthesis. However, a new study showed (in which already once!) That the functions of one of these molecules - molecules are significantly wider: at certain cases they can stimulate the broadcast, rather than block it.
In the past ten to fifteen years, the main dogma of molecular biology ("DNA → RNA → Protein") significantly loosened expanded due to the fact that the great set of molecular mechanisms that are discovered from this slender concept. The discoveries associated with short, non-coding proteins, RNA molecules include: here include the famous RNA interference phenomenon (marked by the Nobel Prize shortly after opening) and other mechanisms for RNA-dependent gene repression. One of the varieties of short RNA - micro-RNA (MirNNA; MIRNA) is actively involved in the processes of individual development of the body, including temporary control, death, proliferation and differentiation of cells, the embryonic laying of organs. They carry out the "fine setting" of gene expression in the post-transcriptional level, thereby adding another level of complexity to the sophisticated intracellular regulation mechanism. Originally open in the "laboratory" nematode C. Elegans., MirNNI was then found in many plants and animals, and relatively recently in single-cell organisms.
It was previously that short RNA were used by cells in the process of RNA interference for specific degradation of non-necessary or harmful RNAs - in particular, so the cell can destroy the alien genetic material of viruses, relatives of them retrotransposons and other mobile elements, as well as RNA resulting from transcription genomic repetitive sequences. Therefore, it was logical to assume that short RNA serve as a kind of prototype of the "immune system" inside the cell. With the development of our ideas about the participants and mechanisms of RNA-dependent repression of genes, all new and new interesting features were found, a rich diversity of the existing paths of this repression existing in nature was revealed.
The mechanism of action of most MIRNA is largely similar to RNA interference - short (21-25 bases) single-chain RNA in the composition of the protein complex (the key component of which is a protein of the family Argonaute.) High specificity associated with a complementary area in the 3'-untranslated area (3'-NTO) mRNA target. In plants, which are completely complementary by the segment of the target mRNA, binding leads to the splitting of mRNA protein Argonaute. Right in the middle of the MRNAK-MRNA Duplex - the situation closest to the "classic" RNA interference. In animals, the MirNK is not fully complementary, and the binding result is obtained by others. For a long time it was believed that binding leads to the suppression of the broadcast (the mechanism of which still remains a mystery) and does not cause any noticeable degradation of the target mRNA. However, it was convincingly demonstrated that for most MiRNA, these are not so - proteins forming a complex with MirNNA, stimulate the degradation of the target mRNA, attracting enzymes that remove the Capper on the 5'-end and the shortening of poly (a) -shore to 3'- The end of mRNA. (From this, the degradation of mRNA, which served their own.) Amazingly, but still not entirely clear whether the reduction of broadcast is the cause or consequence of the start of mRNA degradation.
Meanwhile, life again demonstrates its reluctance to fit into any unambiguous schemes: in the laboratory Joan Styts ( Joan Steitz.) It was found that the MirND can effectively suppress the broadcast, binding not only with the 3'-untranslated area of \u200b\u200bmRNA, but also from 5'-NTO. And recently in the journal Science Another article appeared this successful laboratory. It states that under certain conditions (reminding the cells of the cells in the "winter hibernation", when they are cultivating them in the absence of serum in a nutrient medium), the interaction of MIRNC and MRNA-target leads to a strictly opposite effect - strengthening synthesis Target protein. It was shown for mRNA of one of the cytokines, the necrosis factor α (TNF-α), and MIR369-3 MirNX, and then confirmed for MirNK LET7-A and MIRCXCR4 in a pair with artificially designed mRNA targets.
Figure 1. In an actively divided by a cell, by contacting the complementary sequence in the 3'-untranslated mRNA section, inhibits protein synthesis (broadcast). However, in a resting cell, the same event leads to a direct opposite effect.
Interestingly, the action of the same MIRNA depended on the state of the cells: in the dividing cells of MirNNA, the broadcast of mRNA was oppressed, and in resting (temporarily released from the cell cycle), on the contrary - stimulated (Fig. 1). Curiously the fact that MirNNI acted as part of a complex containing proteins Argonaute 2. and FXR1 (Although the human genome encodes 4 related protein of the family Argonaute.and all of them to one degree or another deal with MirNNA). It is these proteins that owns the main role in the mechanism of the observed phenomenon, while MirNNA perform the function of the "replaceable adapter" through which proteins are interacted with various mRNA targets.
The question of the mechanism of action, as well as the avalanche of other, more specific issues caused by this publication, are still unanswered. But the time is remembered when the phenomenon of RNA-integrity was opened - how then everything was clear to us and what seemed logical to us! .. And now you can only get it with your hands - the further in the forest, the more firewood.
Literature
- Microrn was first discovered in a unicellular body;
- Grigorovich S. (2003). Small RNA in big science. Part 1. Phenomenon of small RNA. Scientific.ru.;
- J. R. Lytle, T. A. Yario, J. A. Steitz. (2007). Target Mrnas Are Repressed AS Efficiently by Microrna-Binding Sites In The 5 "UTR AS IN THE THR" UTR. Proceedings of the National Academy of Sciences. 104 , 9667-9672;
- S. Vasudevan, Y. Tong, J. A. Steitz. (2007). Switching from Repression to Activation: Micrornas Can Up-Regulate Translation. Science. 318 , 1931-1934;
- Nicole Rusk. (2008). When Micrornas Activate Translation. Nat Methods.. 5 , 122-123.
Starting from ancient times, people learned to notice some relationships between different phenomena and analyze them. And then then they still did not mean much, but they found their expression in various proverbs, sayings and statements.
What is the role of folk wisdom in the life of people
Wise thoughts and advice on all occasions that are contained in proverbs accompany us throughout our life. And despite the fact that some proverbs are not one hundred years, they will always be relevant, because the basic vital laws will never change. There are a lot of wise statements, for example: "The farther in the forest, the more firewood," "seems to be not sweet to the tooth," "praised - a young female", "you will live - see, wait - you will hear" and others. All of them briefly and clearly characterize certain actions, relationships, phenomena, give important life advice.
"The further into the forest, the more firewood." The meaning of the proverb
Even in antiquity, without knowing how to count, people have noticed certain patterns. The more game will be achieved on the hunt - the longer time the tribe will not suffer from hunger, the brighter and the fire burns longer - the greater will be in the cave, etc. The farther in the forest, the more firewood is also a fact. On the edge, as a rule, everything is already assembled, but in the deep more often, where the person's leg did not go - there is no wonderless. However, in this saying, there is a much deeper meaning. The forest and firewood do not need to be perceived literally, the people expressed simply the relationship of these concepts of these concepts, which occurred in our lives.
In the proverb "The farther in the forest, the more firewood" the meaning is: the more deeper into any business or the idea, the more the "pitfalls" pops up to the surface. This expression can be applied to many concepts and situations. For example, the deeper you begin to study any question, the more details of it recognize. Or the longer you communicate with a person - the better understand the features of his character.
In what situations most often used the proverb "The further in the forest, the more firewood"
Despite the fact that the meaning of the proverb allows it to be applied in many situations, most often it is used when it comes to the emergence of unforeseen difficulties and complications in any launched. Not in vain in the proverb they say about firewood. Everyone knows that the expression "to block firewood" means "make a mistake, enrolling the haze", that is, it is treated in a disapproving key.
You can apply this proverb not only in relation to some specifically started. "The further into the forest, the more firewood" - so we can say about the person who, for example, is constantly deceiving others, and the lie delays it into a vicious circle, generating all the new and new lies. Or, for example, someone wants to climb the career ladder and for all this is ready for everything. If, to achieve his goal, he leads a dishonest game, the higher it rises along the "steps", the more non-deposition actions he has to do.
Conclusion
The folk wisdom, laid in proverbs and sayings, briefly and is characterized by all sides of life - the relationship between people, attitudes towards nature, human weaknesses and other aspects. All proverbs and wise statements are a real treasure that the people collected in grains not one century and transmitted to future generations. According to proverbs and sayings, you can judge the values \u200b\u200bthat are inherent in different cultures. It is in such statements that the world's vision is as a whole and in various private life situations. It is difficult to overestimate the importance and role of proverbs and sayings in society. They are the spiritual heritage of our ancestors, which we must honor and take care.
Starting from ancient times, people learned to notice some relationships between different phenomena and analyze them. And then then they still did not mean much, but they found their expression in various proverbs, sayings and statements.
What is the role of folk wisdom in the life of people
Wise thoughts and advice on all occasions that are contained in proverbs accompany us throughout our life. And despite the fact that some proverbs are not one hundred years, they will always be relevant, because the basic vital laws will never change. There are a lot of wise statements, for example: "The farther in the forest, the more firewood," "seems to be not sweet to the tooth," "praised - a young female", "you will live - see, wait - you will hear" and others. All of them briefly and clearly characterize certain actions, relationships, phenomena, give important life advice.
"The further into the forest, the more firewood." The meaning of the proverb
Even in antiquity, without knowing how to count, people have noticed certain patterns. The more game will be achieved on the hunt - the longer time the tribe will not suffer from hunger, the brighter and the fire burns longer - the greater will be in the cave, etc. The farther in the forest, the more firewood is also a fact. On the edge, as a rule, everything is already assembled, but in the deep more often, where the person's leg did not go - there is no wonderless.
However, in this saying, there is a much deeper meaning. The forest and firewood do not need to be perceived literally, the people expressed simply the relationship of these concepts of these concepts, which occurred in our lives.
In the proverb "The farther in the forest, the more firewood" the meaning is: the more deeper into any business or the idea, the more the "pitfalls" pops up to the surface. This expression can be applied to many concepts and situations. For example, the deeper you begin to study any question, the more details of it recognize. Or the longer you communicate with a person - the better understand the features of his character.
In what situations most often used the proverb "The further in the forest, the more firewood"
Despite the fact that the meaning of the proverb allows it to be applied in many situations, most often it is used when it comes to the emergence of unforeseen difficulties and complications in any launched. Not in vain in the proverb they say about firewood. Everyone knows that the expression "to block firewood" means "make a mistake, enrolling the haze", that is, it is treated in a disapproving key.
You can apply this proverb not only in relation to some specifically started. "The further into the forest, the more firewood" - so we can say about the person who, for example, is constantly deceiving others, and the lie delays it into a vicious circle, generating all the new and new lies. Or, for example, someone wants to climb the career ladder and for all this is ready for everything. If, to achieve his goal, he leads a dishonest game, the higher it rises along the "steps", the more non-deposition actions he has to do.
Conclusion
The stated in proverbs and sayings, briefly and heels characterizes all parties to life - the relationship between people, the attitude towards nature, human weaknesses and other aspects. All proverbs and wise statements are a real treasure that the people collected in grains not one century and transmitted to future generations. According to proverbs and sayings, you can judge the values \u200b\u200bthat are inherent in different cultures. It is in such statements that the world's vision is as a whole and in various private life situations. It is difficult to overestimate the importance and role of proverbs and sayings in society. They are the spiritual heritage of our ancestors, which we must honor and take care.
Russian proverb, meaning: The deeper you immerse yourself in the problem, it's, etc., the more subtleties and features hidden earlier, discover.
Examples
(1860 - 1904)
"Waterville" (1884): "With the wife of the hysteria. Daughter declares that she is not able to live with such violent parents, and dress up to get out of the house.. Ends the fact that an important guest is cautioned on the stage of the doctor applying to The head of her husband lead grades, and a private bailiff that makes up a protocol on violation of public peace and tranquility. "
"Sakhalin island" - "Cattle, which is, taken from the treasury in debt and feeds on a government account. The farther in the forest, the more firewood: All arkovs must, their debt grows with each new sowing, with each of the head of livestock, and some it extends already to the non-demanding numbers - two and even three hundred rubles per soul. "
(1809 - 1852)
(1831-1832), I - about Ivan Fedorovich Shponyka:
"It was already for him without a small fifteen years, when he switched to the second class, where, instead of the abbreviated Catchism and four arithmetic rules, he began for the most extensive, for the book about the positions of man and for the fraction. But, seeing that the farther in the forest, the more firewoodAnd having received the news that the father ordered to live for a long time, stayed for two more years and, with the consent of the mother, then joined the p *** infantry regiment. "